Our Focus
Kardigan is aiming to shift the cardiovascular treatment paradigm through a modernized approach to drug discovery and development.
Cardiac Intelligence is Kardigan’s proprietary toolkit for precision cardiovascular drug innovation. We believe that the next generation of cardiovascular innovation will be defined by the integration of precision therapeutics and high-fidelity data. To achieve this, we have pioneered “Cardiac Intelligence,” a proprietary toolkit that enables our precision approach at scale by combining deep translational science with advanced technology infrastructure.
The foundation of this toolkit is Prolaio, our clinical intelligence platform of integrated medical insights and data analytics. By coupling Prolaio with our proprietary translational tools, we are able to identify the biological drivers of disease and execute clinical programs with unmatched precision and efficiency in cardiovascular medicine.
We are actively deploying our Cardiac Intelligence toolkit across all stages of our pipeline, using its integrated data and analytics capabilities to accelerate target discovery, optimize clinical trial design and execution and inform precision commercialization strategies for our cardiovascular therapeutics.
The Pillars Driving Cardiac Intelligence
Target Well-Defined Patient Populations
- Develop therapies specifically for biologically defined subgroups rather than one-size-fits-all cardiovascular care
Target the Root Cause
- Focus on biological drivers of disease to enable disease modification beyond symptom relief based on deep mechanistic understanding and continuous learnings to guide program and portfolio decisions
Harness Technology
- Leverage continuous real-world data and AI analytics to increase power, speed and insight
Develop Differently
- Use data-driven and insight-rich strategies and seek to gain early regulatory alignment for novel functional endpoints
Our three late-stage clinical programs cover many key disease mechanisms in the integrated cardiovascular system. Together, they generate new insights and data to fuel Kardigan’s R&D efforts, inform clinical trial design, and potentially reduce the time and cost to develop meaningful new medicines.
The Prolaio Platform
Prolaio is a clinical intelligence platform with integrated medical insights and data analytics designed to improve the efficiency and quality and increase the probability of success of cardiovascular clinical development. By integrating third-party clinical-grade wearable sensors, a patient-friendly user interface, and proprietary Class I and Class II FDA-regulated devices, including 510(k)-cleared algorithms, Prolaio enables continuous physiologic data collection and customized patient-reported outcome information from patients in their daily lives outside of the clinic.
Our Prolaio technology platform is being integrated across our clinical trials to support more continuous, patient-centered data collection.
We believe the Kardigan Prolaio platform is positioned to define and enable the design, execution, and optimization of modern clinical development for precision cardiology.